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Pet Mental Health Guide: Anxiety, Depression & Enrichment (2026) | One Health Globe

Pet Mental Health Guide: Dog Anxiety, Depression, CDS & Enrichment (2026 Vet-Approved)

87% of pet owners say their dog improves their own mental health. But who’s looking after your dog’s mental wellness? Here’s the complete vet-approved guide — from anxiety to Canine Cognitive Dysfunction.

🧠 87% of owners say pets improve their mental health
😰 20–40% of dogs have separation anxiety
🐾 68% of dogs 15+ have CDS
📢 Affiliate Disclosure: This article contains affiliate links. If you purchase through our links, we may earn a commission from our partners at no extra cost to you. Our reviews are vet-reviewed and editorially independent. We only recommend products we genuinely believe in. Full disclosure policy →
⚠️ Veterinary Disclaimer: This guide is for educational purposes only. Behavior changes in dogs — including apparent anxiety, depression, or cognitive decline — often have underlying medical causes that require professional diagnosis. Always consult a licensed vet before starting any treatment protocol for your dog’s mental health. A Dutch Pet licensed vet can evaluate your dog tonight — no waiting room required →

We talk constantly about what pets do for our mental health — but we rarely ask what we’re doing for theirs. Research from the Human-Animal Bond Research Institute (HABRI) confirms that 74% of pet owners report improved mental health thanks to their pets. Yet millions of those same pets are living with unaddressed anxiety, chronic boredom, grief, or the early stages of cognitive decline that their owners simply haven’t recognized.

Dogs experience a rich emotional life. Veterinary behaviorists at the AVMA, ASPCA, and Cornell University’s College of Veterinary Medicine all affirm that dogs feel anxiety, fear, grief, and depression-like states. They communicate these emotions not through words, but through changes in behavior — changes that are all too easy to misread or miss entirely. Our team consulted with licensed veterinary behaviorists to bring you this complete 2026 guide to canine mental wellness.

Start with our Free Dog Paw Scanner to check for any physical pain that may be masking itself as behavioral change, and keep our Pet Vaccine Tracker current — immune health and neurological health are closely linked in dogs.

87%
of pet owners report dogs have a positive impact on their own mental health
40%
of dogs seen by behaviorists have separation anxiety symptoms
68%
of dogs aged 15–16 show signs of Canine Cognitive Dysfunction
74%
of pet owners report improved mental health thanks to their pets (HABRI)

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The 3 Core Canine Mental Health Conditions Every Owner Must Know

Dog mental health is not a single issue — it is a spectrum of distinct conditions, each with different causes, signs, and treatment approaches. Misidentifying which condition your dog has leads to ineffective management that can make the underlying problem worse. Here are the three most important:

😰
Anxiety Disorders
The most common canine mental health problem. Ranges from situational fear (thunderstorms, fireworks) to chronic generalized anxiety and separation anxiety. Affects 20–40% of dogs seen by veterinary behaviorists. Driven by an overactivated stress response — the dog perceives threat where none exists.
💜
Depression-Like States
Not a formal veterinary diagnosis, but a recognized clinical pattern of sustained low mood, withdrawal, and reduced engagement. Triggered by major life changes: loss of a companion (animal or human), rehoming, schedule disruption, or chronic pain. Commonly confused with illness — always rule out medical causes first.
🧠
Canine Cognitive Dysfunction (CDS)
The canine equivalent of Alzheimer’s disease. Beta-amyloid plaques accumulate in the aging brain, causing progressive cognitive decline. Affects 28% of dogs aged 11–12 and 68% of dogs aged 15–16. Massively underdiagnosed — fewer than 2% of affected dogs receive a formal diagnosis because owners attribute signs to “normal aging.”
🔬 The Science of Canine Emotions: Neuroscientist Gregory Berns’ MRI research at Emory University confirmed that the caudate nucleus — the brain’s reward center — activates in dogs in response to human praise and familiar scents, the same way it activates in humans experiencing positive emotions. Dogs are not “just reacting” — they are genuinely feeling.

How to Read Your Dog’s Mental Health: Signs by Condition

Because dogs cannot speak, their mental distress is expressed entirely through behavior — body language, changes in routine, and shifts in personality. The challenge is that many of these signs overlap across conditions, and they also overlap significantly with physical illness. A vet evaluation is always the first step when you notice any sustained behavioral change.

Signs of Anxiety in Dogs

!
Restlessness — pacing, inability to settle even in familiar environments
!
Panting without physical exertion or heat exposure
!
Excessive yawning, lip-licking, or whale-eye (whites of eyes visible)
!
Hiding, cowering, or attempting to escape confined spaces
!
Destructive behavior when left alone — chewing, digging, scratching doors
!
House soiling in previously reliable dogs
!
Excessive barking or howling when alone or triggered
!
Trembling, tail tucking, or ears pinned back

Signs of Depression-Like States in Dogs

!
Persistent low energy — sleeping more than usual, reluctance to get up
!
Loss of interest in toys, walks, or activities previously enjoyed
!
Social withdrawal from family — seeking solitude instead of company
!
Reduced appetite or changes in eating pattern
!
Flat affect — tail not wagging, face lacking normal expressiveness
!
Excessive sleeping during hours the dog was previously active

Signs of Canine Cognitive Dysfunction (CDS)

!
Disorientation in familiar spaces — getting lost in corners, staring at walls
!
Nighttime restlessness — pacing, vocalizing, unsettled after dark
!
Forgetting trained behaviors — sit, stay, housetraining failures
!
Reduced social interaction — less interested in family and play
!
Aimless wandering — circling, appearing confused with no clear purpose
!
Personality changes — increased irritability, anxiety, or clinginess
💡 Critical Reminder: Pain, thyroid disease, urinary infections, liver disease, and neurological disorders all mimic mental health symptoms in dogs. Never assume a behavioral change is emotional until a vet has ruled out a medical cause. A Dutch Pet licensed vet can screen for these conditions tonight via video — 24/7, no appointment needed.

What Causes Mental Health Problems in Dogs — And Who Is Most at Risk

Understanding the root causes of canine mental health problems helps owners both prevent them and respond more effectively when they arise.

Genetic Predisposition

Certain breeds carry higher baseline anxiety due to selective breeding history. Border Collies, German Shepherds, and Vizslas were bred to work in close contact with humans all day — isolation triggers significant distress in these breeds. Brachycephalic breeds (Bulldogs, Frenchies) experience higher baseline physiological stress due to respiratory effort. Greyhounds and other sight hounds often have high noise sensitivity. Knowing your breed’s predispositions sets realistic expectations.

Early Life Experiences

The socialization window (8–16 weeks) shapes a dog’s emotional resilience for life. Dogs inadequately socialized during this window are significantly more prone to anxiety, reactivity, and fear-based behavior as adults. Rescue dogs with unknown or traumatic backgrounds carry the highest risk of anxiety disorders — research suggests 60–70% of rescue dogs show some anxiety-related behaviors in the first year after adoption.

Life Disruptions and Loss

Dogs form genuine attachment bonds — with their owners, with other household pets, and with their routines. The loss of a companion animal or a beloved person, a move to a new home, a change in the owner’s work schedule, or the arrival of a new baby or pet are all recognized triggers for depression-like states and increased anxiety in dogs. The ASPCA recognizes grief as a real emotional experience for dogs.

Chronic Pain and Illness

Pain changes behavior. A dog with undiagnosed arthritis who snaps when touched, withdraws from play, or becomes house-soiled is expressing physical suffering in behavioral terms. Chronic illness — kidney disease, thyroid disorders, neurological conditions — all carry secondary effects on mood, energy, and emotional regulation. This is why every behavioral evaluation must begin with a physical health assessment.

Under-Stimulation and Boredom

The modern domestic dog is a highly intelligent, social, working-lineage animal living in a largely sedentary, isolated environment. Mental under-stimulation is one of the most overlooked causes of canine behavioral and emotional problems. A bored dog is not a lazy dog — a bored dog is a dog whose cognitive and social needs are going unmet, and whose resulting frustration expresses as destructive behavior, anxiety, and reduced wellbeing.

The 5 Pillars of Canine Mental Wellness

Veterinary behaviorists and animal welfare organizations converge on five core pillars that form the foundation of healthy dog mental health. A dog who receives all five consistently is dramatically less likely to develop anxiety, depression-like states, or behavioral problems than one who lacks any one of them.

🔄
Consistent Routine
Dogs are creatures of predictability. Regular feeding times, walk schedules, and sleep routines reduce baseline cortisol and create the psychological safety that allows dogs to relax. Unpredictable schedules are a significant contributor to chronic anxiety.
🏃
Daily Exercise
Physical exercise releases endorphins and serotonin, reduces cortisol, and depletes the excess energy that expresses as restlessness and destructive behavior. The minimum for most dogs: 30–60 minutes of intentional movement daily, not just a backyard wander.
🧩
Mental Enrichment
A 15-minute puzzle feeding session tires a dog more than a 45-minute walk. Problem-solving engages the prefrontal cortex, builds confidence, and provides the cognitive satisfaction dogs were bred to experience through work. This pillar is the most commonly neglected.
🤝
Positive Social Interaction
Dogs are social animals. Meaningful daily interaction — not just physical presence — with their owners, and appropriate controlled exposure to other dogs, is essential for emotional balance. Quality matters more than quantity: 10 focused minutes of training is more valuable than 8 hours of ignored coexistence.
🌿
Nutritional Brain Support
Omega-3 fatty acids (EPA and DHA) support brain membrane integrity and reduce neuroinflammation. B vitamins are essential for neurotransmitter synthesis. Probiotics support the gut-brain axis — research shows gut microbiome composition directly influences anxiety levels. A daily supplement that covers all three is the simplest nutritional investment in your dog’s mental health.
1

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Bailey’s CBD Calming Oil interacts directly with your dog’s endocannabinoid system (ECS) — a network of receptors throughout the brain, nervous system, and gut that regulates mood, fear response, sleep cycles, and emotional balance. Full-spectrum CBD from certified organic US hemp provides the full entourage effect, meaning all naturally occurring cannabinoids work together to provide broader physiological support than CBD isolate alone.

Research published in Frontiers in Veterinary Science found that dogs given CBD at 4mg/kg showed significantly lower cortisol levels, reduced stress vocalization, and lower anxiety scores compared to placebo during separation events and car travel. For dogs experiencing grief, routine disruption, or chronic low-grade anxiety, Bailey’s provides genuine physiological support — not just behavioral management — making the other four wellness pillars easier to maintain.

✅ PROS
  • Full-spectrum CBD — broadest entourage effect
  • Certified organic US hemp — no pesticides
  • Cortisol reduction confirmed in veterinary research
  • Non-sedating — dog remains alert and engaged
  • Third-party lab tested for potency and purity
  • Precise oil dosing — easy to adjust per body weight
❌ CONS
  • Wellness supplement — not an FDA-approved drug. Pair with vet consult for severe anxiety
  • Takes 30–45 min for full effect — plan ahead for known triggers
🌿 Is Your Dog’s Anxiety Holding Them Back?

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12 Vet-Approved Mental Enrichment Activities for Dogs (2026)

Mental stimulation is not optional — it is a core health need. Veterinary behaviorists consistently find that a mentally enriched dog has measurably lower cortisol, fewer anxiety-driven behaviors, and greater emotional resilience than an under-stimulated dog receiving the same amount of physical exercise. These 12 activities are organized by difficulty to help you build a varied weekly enrichment plan:

Easy — Start Here
🐾 Sniff Walks (Sniffaris)
Let your dog lead on a slow walk, stopping to sniff as long as they want. A dog’s nose processes 300x more scent information than ours — a 20-minute sniff walk is more mentally tiring than a 60-minute run.
⏱ 15–30 min · Daily
Easy
🧊 Frozen Kongs / Lick Mats
Fill a Kong with peanut butter (xylitol-free), banana, or wet food and freeze overnight. The extended licking motion releases serotonin and creates sustained calm focus. Ideal for departure anxiety preparation.
⏱ 10–20 min · Pre-departure or daily
Easy
🍽️ Scatter Feeding
Instead of a bowl, scatter your dog’s kibble across the grass or a snuffle mat. Uses natural foraging instinct. Slows eating, reduces bloat risk, and provides 10–15 minutes of focused scent work from a single meal.
⏱ 10–15 min · Daily with meals
Easy
🎯 Name That Toy
Teach your dog the names of their toys one at a time. Ask them to fetch a specific toy by name. Border Collies can learn 200+ object names. All breeds benefit from the problem-solving challenge and vocabulary building.
⏱ 5–10 min · 3× per week
Moderate
🧩 Puzzle Feeders
Nina Ottosson-style sliding puzzles, treat mazes, and shell games require dogs to problem-solve for food rewards. Start at beginner level and progress — solved-too-quickly puzzles provide no enrichment value. Rotate between different puzzles weekly.
⏱ 10–15 min · Daily
Moderate
🫙 Muffin Tin Game
Place treats in some cups of a muffin tin, cover all cups with tennis balls. Your dog learns to remove balls to find the reward. Easy DIY puzzle using household items — great for beginners before introducing commercial puzzles.
⏱ 5–10 min · Daily
Moderate
👃 Nose Work / Scent Detection
Hide a specific scent (birch oil is the K9 Nose Work standard) in boxes, then rooms, then outdoors. Dogs self-reward by locating the scent — no trainer needed once the foundation is established. Ideal for anxious and reactive dogs as it builds confidence through success.
⏱ 10–20 min · 3–5× per week
Moderate
🎲 Which Hand? (Choice Game)
Hold a treat in one closed fist. Let dog sniff both hands. When they indicate the correct hand (nose touch, paw), open it for the reward. Simple but highly engaging — teaches dogs that offering calm, deliberate behavior produces good outcomes.
⏱ 5 min · Daily warm-up
Moderate
🏠 Indoor Treasure Hunt
Hide kibble, pieces of cheese, or small toys around the house while your dog waits in another room. Release them to “find it.” Progress to harder hiding spots and multiple items. Engages natural scavenging drive in a safe, structured way.
⏱ 10–15 min · 3× per week
Advanced
🏅 New Trick Training
Teach one new trick per week — spin, bow, roll over, figure-8 between legs. Use exclusively positive reinforcement. Learning new behaviors activates the brain’s reward system and creates a focused, satisfied mental state. Dogs are never “too old” to learn new tricks.
⏱ 5–10 min · Daily
Advanced
🐕 Dog Sports (Agility, Rally)
Agility, Rally Obedience, and Treibball (urban herding) provide the highest level of combined physical and mental challenge. Particularly beneficial for working breeds. Community classes provide the added benefit of positive social interaction for both dog and owner.
⏱ 60 min class · Weekly
Advanced
📦 Box Training (Free Shaping)
Place an open cardboard box on the floor and wait. Click and reward any interaction with the box — sniffing, pawing, stepping in. Let the dog discover that their own choices produce rewards. This “free shaping” method builds tremendous problem-solving confidence and is highly mentally engaging.
⏱ 5 min · Per session
💡 Enrichment Rotation Rule: Repeat the same activity for 3–4 consecutive days to allow mastery, then rotate to a new one. Dogs show peak engagement with novel challenges and reduced engagement with over-familiar ones. Keep a written enrichment log and rotate across all five enrichment categories (sensory, cognitive, physical, social, feeding) throughout each week.

Canine Cognitive Dysfunction: The Silent Epidemic in Senior Dogs

CDS is one of the most underdiagnosed conditions in veterinary medicine. Research published in the American Journal of Veterinary Research (2025) documents that fewer than 2% of CDS-affected dogs receive a formal diagnosis, because owners — and sometimes even vets — attribute early signs to “normal aging.” This matters enormously: early diagnosis and management significantly slow progression and improve quality of life.

The 2026 guidelines from the CCDS Working Group, published in the Journal of the American Veterinary Medical Association, established the first standardized diagnostic framework using six behavioral domains: disorientation, impaired social interactions, sleep disturbances, house soiling, learning and memory deficits, and changes in activity level.

The DISHAA Checklist: Assess Your Senior Dog at Home

Use this structured checklist for any dog over 8 years old. If you notice changes in two or more categories sustained over 4+ weeks, schedule a veterinary evaluation promptly:

  • D — Disorientation: Gets lost in familiar spaces, stares at walls or into corners, gets “stuck” behind furniture
  • I — Interactions changed: Seeks less human attention, reduced greeting behavior, more irritable with family members or other pets
  • S — Sleep-wake cycles altered: Restless at night, pacing after dark, sleeping more during the day
  • H — House soiling: Accidents in a previously reliable dog — especially overnight or when close to the door
  • A — Activity changes: Less interest in play, walks, or exploration; aimless wandering; increased repetitive behaviors
  • A — Anxiety increased: New separation distress, increased vocalization, clingy behavior, heightened startle response
🧠 CDS Prevalence by Age: Research consistently shows CDS affects approximately 14% of dogs over 8 years, 28% of dogs aged 11–12, and up to 68% of dogs aged 15–16. The disease can begin as early as age 7 in some large breeds. Given that the average US household dog is 5.2 years old and expected to live to 12–15 years, CDS will affect the majority of dogs currently living as pets — making early awareness critical.
2

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🩺 Best For: Senior dogs showing CDS signs · Severe anxiety not responding to supplements · Rx evaluation

For senior dogs showing CDS signs, dogs with moderate-to-severe anxiety, or dogs whose behavioral problems have a suspected medical component, a licensed veterinary consultation is not optional — it is essential. Dutch Pet connects you with a licensed US vet via video within minutes, 24/7, without a clinic appointment, waiting room, or transportation stress.

Dutch Pet vets can order blood panels to screen for thyroid disease, kidney disease, and other conditions mimicking mental health symptoms. They can prescribe FDA-approved behavioral medications — including fluoxetine (the only FDA-approved drug specifically for canine separation anxiety), trazodone, or clomipramine — and cognitive support supplements. For CDS specifically, they can recommend Anipryl (selegiline), the only FDA-approved drug for canine cognitive dysfunction.

✅ PROS
  • Licensed US vets — 24/7 availability, no appointment
  • Prescription access to FDA-approved behavioral Rx
  • Can order diagnostic blood panels remotely
  • CDS-specific treatment recommendations available
  • No transportation stress for anxious dogs
  • Same-night consultation and Rx if appropriate
❌ CONS
  • Physical exam requires an in-person vet for complete assessment
  • Consultation fee applies — check current pricing on the Dutch website
3

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🌿 Best For: Daily brain health foundation — all ages, especially seniors and anxious dogs

Mental health is downstream of nutrition. The brain requires specific nutrients to produce neurotransmitters, regulate inflammation, and maintain the myelin sheaths that enable efficient neural signaling. Ruff Greens VitaSmart delivers 25 vitamins, 15 probiotics, and Omega-3 oils in a single daily food topper — creating the nutritional foundation for both emotional resilience and cognitive health.

The Omega-3s (EPA and DHA) are particularly critical: research shows they reduce neuroinflammation and support the brain membrane integrity that declines with age and stress. The probiotics address the gut-brain axis — veterinary research increasingly confirms that gut microbiome composition directly influences anxiety levels and serotonin production. For senior dogs showing early CDS signs, the antioxidant vitamins help neutralize the oxidative stress that accelerates beta-amyloid accumulation.

✅ PROS
  • Free trial — just $9.95 shipping, zero risk
  • Omega-3s (EPA/DHA) for brain membrane support
  • 15 probiotics support the gut-brain anxiety axis
  • Antioxidant vitamins reduce oxidative brain stress
  • B vitamins essential for neurotransmitter synthesis
  • 200,000+ dogs using it — including many seniors
❌ CONS
  • Foundational support — not a standalone anxiety treatment
  • Picky eaters may need 1–2 weeks to fully accept

When Your Dog’s Mental Health Requires Professional Help

Home management works well for mild anxiety, situational stress, and boredom-driven behaviors. These situations require veterinary or specialist intervention:

  • Any sudden behavioral change in a dog with no recent life disruption — sudden aggression, confusion, or personality shifts warrant same-day veterinary evaluation for neurological causes
  • Self-injury from anxiety — excessive licking to the point of hot spots, door-scratching causing bleeding, destructive behavior causing injury to the dog
  • CDS signs in any dog over 8 — the sooner CDS is diagnosed, the more effective the management options available
  • Grief unresolved after 6–8 weeks — if a dog has not returned to baseline energy and engagement 6+ weeks after loss, a vet assessment is warranted
  • Anxiety not responding to supplements and behavioral modification after 8 weeks — may require prescription medication alongside behavioral work
  • Any dog that has shown aggression toward a person — requires evaluation by a Certified Veterinary Behaviorist (DACVB) before any other intervention
🚨 Emergency Behavioral Signs: Sudden, unprovoked aggression — especially in a dog with no history of aggression — can indicate a neurological emergency, including seizure disorder, brain lesion, or acute hormonal crisis. Treat this as a medical emergency and contact a veterinary emergency clinic immediately. Do not attempt behavior modification before medical clearance.

Frequently Asked Questions: Pet Mental Health

Can dogs feel anxiety and depression?
Yes. Veterinary behaviorists and organizations including the ASPCA and AVMA recognize that dogs experience a range of emotions including anxiety, fear, grief, and depression-like states. Dogs don’t express these verbally — they communicate through behavior changes such as reduced activity, appetite changes, withdrawal from family, excessive vocalization, and destructive behavior. Any sustained behavioral change warrants a veterinary evaluation to rule out medical causes first.
What are the signs of anxiety in dogs?
Common signs include: restlessness or inability to settle, panting without physical exertion, excessive yawning or lip-licking, pacing, hiding or escape attempts, excessive barking or howling, destructive behavior when alone, house soiling in previously reliable dogs, reduced appetite, trembling, and tail tucking. Anxiety ranges from mild situational stress to chronic generalized anxiety. A veterinary evaluation is essential to determine the type and severity and rule out physical pain as the underlying cause.
What is Canine Cognitive Dysfunction Syndrome (CDS)?
CDS is an age-related neurodegenerative condition similar to Alzheimer’s disease. Beta-amyloid protein accumulates in the aging brain, causing progressive cognitive decline. It affects 28% of dogs aged 11–12 and up to 68% of dogs aged 15–16. Signs include disorientation in familiar surroundings, nighttime restlessness, reduced social interaction, house soiling, increased anxiety, and apparent forgetting of trained behaviors. CDS is frequently misidentified as “normal aging” — if you notice these signs, consult a vet promptly for diagnosis and management options.
How can I improve my dog’s mental health at home?
Focus on the five pillars: consistent daily routine, daily physical exercise, mental enrichment activities (puzzle feeders, scent work, training games), positive social interaction, and nutritional brain support. For anxiety-driven problems, vet-formulated calming supplements like Bailey’s CBD Oil or Dutch Pet Calming Supplement provide additional physiological support. For senior dogs, a daily supplement with Omega-3s and antioxidants like Ruff Greens VitaSmart supports the cognitive health that mental engagement requires.
When does dog anxiety require medication?
Medication is appropriate when anxiety is severe enough to cause self-injury or property destruction, when the dog cannot settle or learn due to constant arousal, when separation anxiety doesn’t respond to behavioral modification over 8+ weeks, or when anxiety is linked to CDS. FDA-approved options include fluoxetine (the only FDA-approved drug specifically for canine separation anxiety) and clomipramine. A Dutch Pet licensed vet can evaluate your dog and prescribe appropriate treatment tonight via video consultation — 24/7, no appointment needed.

Your Dog Deserves Mental Wellness Too

The complete approach: implement all five wellness pillars daily → support anxiety with Bailey’s CBD Calming Oil → ensure nutritional brain health with Ruff Greens VitaSmart → get a Dutch Pet vet consult for CDS screening, severe anxiety, or any sudden behavioral change. Your dog gives you their emotional best every day — give them yours in return.

⚕️ Medical Disclaimer: This article is for educational purposes only. It does not constitute veterinary advice, diagnosis, or treatment. Any dog displaying sudden behavioral changes, aggression, or signs of cognitive dysfunction should be evaluated by a licensed veterinarian immediately. If your dog is in distress, contact your nearest veterinary emergency clinic.
About the Author & Review Process: This article was written by the One Health Globe editorial team and reviewed by our veterinary advisory panel for factual accuracy. We cross-reference the AVMA, ASPCA, Cornell University College of Veterinary Medicine, the Human-Animal Bond Research Institute (HABRI), the American Journal of Veterinary Research, and Journal of the American Veterinary Medical Association (JAVMA) guidelines for all mental health and behavioral claims. Affiliate relationships do not influence our editorial recommendations. Learn about our review process →
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